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Ranking the best blood sugar supplements of 2022

Blood sugar supplements are designed to support your body’s natural blood sugar regulation. Blood sugar is a vital part of our health. If it gets thrown off, we can develop diabetes.

A surprisingly high percentage of the population already has prediabetes, though most of the time, this disease goes undiagnosed (1).

You can support your body’s natural ability to regulate your blood sugar with a supporting supplement. While these supplements won’t cure diabetes or prediabetes, they can be helpful alongside a dietary change.

Here are some of the best supplements on the market for regulating blood sugar:


1. GluControl

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GluControl is specifically designed to help maintain healthy blood sugar levels. It uses a targeted blend of all-natural ingredients, including cinnamon, lion’s mane, and milk thistle, to better regulate blood sugar, all without extraneous ingredients. This precision blend makes it our number one pick.

2. Dr. Bo Glucose Support

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Dr. Bo incorporates a diverse blend of vitamins, minerals, and supplemental extracts, and the ingredients it uses do a great job covering all your bases from boosting fat oxidation to exerting tighter control over glucose levels.

It’s an especially good choice for people dieting to lose weight, since its inclusion of ingredients like cayenne pepper and L-taurine are thought to have effects on fat oxidation. 

3. NOW Glucose Metabolic Support

NOW Glucose Metabolic Support

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NOW is a popular supplement brand, and this particular supplement is designed to support your blood sugar and metabolic rate. It includes a variety of ingredients, including Gymnema extract.

Unlike most blood sugar supplements, this one does not rely on cinnamon. If other supplements haven’t worked for you, this one may be worth trying since it uses different ingredients.

5. Hyperbiotics Glucose Support

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Inspired by the latest research on the relationship between gut bacteria and glucose control, Hyperbiotics uses a blend of seven different probiotic bacteria plus banaba leaf extract and vitamin D.

It’s a blend of ingredients designed to work alongside the probiotics, making it a solid choice if you want a more advanced approach to glucose control. 

5. Arazo Blood Sugar Support

Blood Sugar Support

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This is another scientifically formulated supplement that includes 20 different ingredients. It features a unique combination of ingredients like licorice, cayenne, and juniper berry.

While this supplement is designed to support your blood sugar levels first and foremost, it can also support weight loss and reduce sugar absorption.

6. Premium Blood Sugar Support Supplement by PurePremium

Premium Blood Sugar Support Supplement by PurePremium

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PurePremium uses a blend of conventional vitamins and minerals, like vitamin C, vitamin E, magnesium, zinc, and chromium, alongside a selection of glucose-oriented supplements: banaba, guggul, bitter melon, and cinnamon being the principal ones.

As with some of the other broad-based glucose control supplements, it’s a good fallback if more focused supplements aren’t giving you the results you want. 

7. Blood Sugar Lowering Supplement by AmericonPlus

Blood Sugar Lowering Supplement by AmericonPlus

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This blood sugar supplement contains many different ingredients, including cinnamon, chromium, and white mulberry leaf extract. Because it includes so many different ingredients, it may work for you when other supplements have not.

It aims to make your blood sugar more consistent and is formulated to be taken with every meal.

8. Premium Blood Sugar Support Supplement by Sunergetic

Premium Blood Sugar Support Supplement by Sunergetic

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With cinnamon and a variety of other herbs, this supplement can support your blood sugar levels and overall health. It features a unique blend of over 15 herbs, including things like yarrow flower and cinnamon.

Plus, this supplement is made in a GMP-certified facility.

9. Nutrivein Premium Berberine

Nutrivein Premium Berberine

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This supplement relies mostly on cinnamon and berberine to work. Both of these ingredients are proven to work in a scientific setting, but they may not work for everyone.

Still, if you’ve never tried a blood sugar review previously, this one may work appropriately for you. Plus, it’s inexpensive.

10. LifeSeasons Glucose Stabili-T

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LifeSeasons takes a multi-ingredient approach to glucose control, leaning on extracts both from common supplements like fenugreek, cinnamon, and banaba, to more obscure ingredients like vanadium, holy basil, and gotu kola leaf, for its glucose control effects.

This broad-based approach might be worth a shot if simpler blood sugar supplements with fewer ingredients aren’t cutting it for you. 

Category winners

Best blood sugar supplement overall: Essential Elements GluControl

Essential Elements uses a blend of natural extracts from cinnamon, berberine, milk thistle, and lion’s mane, plus metabolism-boosting supplements like chromium picolinate, to modulate glucose balance in your body. The comprehensive approach to this blood sugar supplement makes it our top recommendation. 

Best blood sugar supplement for the keto diet: Essential Elements GluControl

If you want to ensure your glucose control is optimized when on the keto diet, the carefully-designed ingredients in Essential Elements GluControl is the way to go. With potent compounds like cinnamon extract, lion’s mane mushroom, and milk thistle seed, it’s built for the kind of metabolic flexibility you need for the ketogenic diet. 

Best blood sugar supplement for women: NOW Glucose Metabolic Support

NOW Glucose Metabolic Support’s use of B vitamins plus banaba, gymnema sylvestre, and a few trace minerals makes it a focused glucose control supplement that’s great for women looking for a targeted approach that integrates well with other supplements. 

Best blood sugar supplement with cinnamon: Essential Elements GluControl

Cinnamon extract exerts a surprising amount of influence on glucose metabolism, and it’s one of the simplest and most well-known supplements for blood sugar control. Essential Elements GluControl does a great job of integrating the effects of cinnamon alongside other glucose control supplements, so if you want a supplement for metabolic control that leverages cinnamon, look no further than Essential Elements. 

Best blood sugar supplement for weight loss: Dr. Bo Glucose Support

If you’re on a diet, Dr. Bo is a great choice since many of its ingredients are designed to both exert glucose control and boost fat oxidation. Its inclusion of both cayenne pepper and L-taurine is especially helpful in this department, which make it our recommendation for people looking to lose weight. 

Best blood sugar supplement with probiotics: Hyperbiotics Glucose Support

Gut bacteria have a big impact on how your body absorbs carbohydrates, which in turn affects your blood sugar. When it comes to blood sugar supplements that leverage the benefits of probiotic bacteria, there’s no better option than Hyperbiotics Glucose Support. With five billion colony-forming units of  seven strains of probiotic bacteria plus banaba leaf and vitamin D, it’s the best supplement for leveraging gut bacteria for metabolic health. 

Who should buy a blood sugar supplement?

Blood sugar supplements are designed to help your body naturally regulate your blood sugar. They are particularly helpful for those with prediabetes or diabetes who are trying to control their disease using diet and exercise.

These pills are not a cure for diabetes, but their natural ingredients can help control your blood sugar and evening it out.

Of course, just like any medication, some supplements may work wonders for you, while others might not work at all. We highly recommend trying out multiple supplements before you dismiss them all.

If you already have diabetes and are on medication, discuss these supplements with your doctor. Some ingredients can interfere with diabetes medication since both are performing the same job. Plus, you may need to decrease your medication at some point as the supplements begin to take effect.

While these supplements are mostly for treating and managing prediabetes and diabetes, they may also help those who are overweight lose a bit of weight. Many have the added side effect of lowering the absorption rate of sugar and carbohydrates, which can lower the number of calories your body absorbs.

Furthermore, many of these supplements also increase your metabolic rate. This may help you burn more calories than you would otherwise, which can lead to higher levels of weight loss.

How we ranked

When we looked at each supplement, the first factor we considered what how safe that supplement was. While we would like all supplements to be upheld to the same safety standards, that just doesn’t happen in reality. The FDA does not regulate these supplements, which means they are made to varying standards.

The safest supplements are those that are made in FDA-certified labs and facilities. While the supplements themselves aren’t regulated, FDA-certified facilities are. This makes them significantly safer than other supplements.

We also aimed to only used supplements that were made in the USA, UK, or Australia. In these countries, certain dangerous ingredients are banned. This is not true for all countries, though, which is why it is essential to only purchase from countries with strict regulations.

After checking for safety, we considered how effective the supplement was. Many of the supplements on our list include cinnamon and other scientifically-proven ingredients. Because these ingredients have been tested and proven in a scientific setting, we preferred supplements that included them.

We also took a look at the customer reviews. While these aren’t always accurate, a lot of bad reviews are a warning sign – while a lot of good reviews may be a reason to rank a product even higher.

Finally, the ease of use and dosage amounts are also important. In general, most people don’t want to take multiple pills a day. However, some supplements are designed to be taken with every meal.

Generally, we ranked these supplements lower than others, just because it was going to be more challenging to take them properly.


Blood sugar supplements contain cinnamon. Studies have shown that cinnamon can improve diabetes control (2).

One particular study found that people with prediabetes experienced an 8.4% decrease in their fasting blood sugar after taking 250 mg of cinnamon before breakfast and dinner for three months (3). That is a substantial decrease. For some participants, it was enough to take them out of the prediabetes category.

Another study followed people with type 2 diabetes. These participants took either 120 mg or 360 mg of cinnamon before breakfast for three months. At the end of the study, they experienced an 11% or 14% reduction in fasting blood sugar, respectively (4).

Furthermore, this study found that their blood sugar average over three-months decreased by about 0.67% to 0.92%.

Cinnamon works in this manner because it improves your body’s response to insulin. This means that your body has to produce less insulin to work, which is essential if you have diabetes. Furthermore, this also allows your cells to absorb sugars easier and at a faster rate, which brings down your blood sugar levels even more.

One point of interest is that regular cinnamon contains quite a bit of coumarin, which can harm your liver. Luckily, the Ceylon variety of cinnamon contains much less coumarin. Most of the supplements we reviewed contain Ceylon cinnamon for this reason.

Blood sugar supplements contain berberine. Berberine is another common ingredient in blood sugar supplements because it can help lower your blood sugar according to a few scientific studies.

One extensive study review that looked at 27 different studies found that people with type 2 diabetes who took berberine alongside diet and lifestyle changes experienced a reduction in fasting blood sugar by about 15.5 mg/dl. This is a significant drop (5).

This review also noted that taking berberine alongside diabetes medication lowered participant’s blood sugar significantly more than just medication alone.

Berberine is thought to help with blood sugar because it may improve insulin sensitivity and help sugar pass into your muscles easier (6).

Our only point of contention with berberine is that it needs to be taken a few times a day with meals to work correctly. Otherwise, you won’t see significant results. Furthermore, this extract may also cause digestive disturbances, including constipation, gas, and diarrhea. For this reason, a lower dose of 300 mg is often recommended.

Berberine can also interact with a few medications, so it is essential to check with your doctor before taking it.

Blood sugar supplements are natural. Perhaps the most significant benefit of blood sugar supplements is that they are effortless to take. It requires very little planning to take a pill every morning. Even if you choose a supplement that requires you to take a dose multiple times a day, that is still much easier than some of the other methods of balancing blood sugar.

Blood sugar supplements are so easy and accessible that they are often paired with other methods of lowering blood sugar as well, such as dietary changes and exercise. Studies have shown that they work even better when used alongside these other methods.

If you have high blood sugar, there is very little reason not to take a blood sugar supplement. They’re easy to take and accessible to nearly everyone.

Blood sugar supplements may help you lose weight. In some cases, the supplements we included in our review may also help you lose weight. Many claim to improve your metabolic rate, which can increase the number of calories you burn daily.

Plus, when your blood sugar is more balanced, you’re less likely to experience cravings and binge on snacks – which is common when your blood sugar gets too low. With this snacking gone from your diet, you may be able to lose weight more quickly.

Obesity does increase your chance of diabetes and prediabetes. So, these supplements might help you even more by lowering your weight as well as balancing out your blood sugar. It is a win-win situation.

Blood sugar supplements contain a variety of ingredients. While most supplements use berberine or cinnamon to reduce your blood sugar levels, this is not true for all supplements. Some use a variety of other ingredients that have varying levels of effectiveness.

However, this isn’t necessarily a bad thing. Because there are so many supplements out there that use a variety of ingredients, it is possible to find one that works for you even if the usual ingredients don’t.

With that said, it often takes up to three months for a supplement to begin working. You may not see the full results until you’ve been taking one particular supplement regularly for a few months; it takes a bit before it builds up enough in your bloodstream. Because of this, you need to try one supplement for a while before switching to a new one.

Still, it is a massive bonus that there are other supplements available for you to switch to.

Side effects

Blood sugar supplements may interact with certain medications. If you’re on a separate medication for your blood sugar levels, some of these supplements may interact. Having blood sugar that is too low is potentially deadly. If your blood sugar stays too low for too long, you can enter a coma and potentially die.

Because of this, it is essential to use these supplements by themselves. If you’re on some sort of other diabetic medication, you should work closely with your doctor to use the correct dosages. Your diabetic medication may need to be lowered as you use these supplements as well, so be sure to mention that you’re taking them to your doctor.

Blood sugar supplements are not a cure. While we all wish we could cure diabetes and prediabetes with a pill, this is not possible. These supplements can help you manage your blood sugar and keep it at a safe level. However, they are not going to be a complete cure for your condition. Insulin and other medication will likely be necessary.

With all these treatments together, though, you may find yourself managing your situation better than you could otherwise.

We recommend using these supplements carefully and alongside your usual medication. Speak with your doctor if you’re afraid of any interactions or if you think your medication might need to be lowered.

Blood sugar supplements don’t work for everyone. While some studies did find positive effects on blood sugar levels when using these supplements, this was not true for everyone. Some studies found little to no effect (7).

You may try a supplement and not experience anything. If this happens, feel free to try another since many do contain different ingredients. Some ingredients work better for some people than others, so it may take some experimentation to discover a supplement that will work for you. Keep in mind that it may take up to three months for a supplement to begin working as well. You should stick with a single supplement for at least three months before switching to something else.

Recommended dosage

There are quite a few different ingredients that blood sugar supplements can contain. Each of these ingredients has its important dosage information. Of course, the potency matters as well, which can vary quite a bit from supplement to supplement.

You should follow the dosage instructions on the back of the supplement bottle that you decide to use. Each company will have its own dosage information depending on what is in their pills and the potency of their ingredients. Some require only one pill a day, while others require that their pills be taken with food.

If your supplement calls for you to take it alongside a meal, you must follow these instructions as carefully as possible. If you don’t, you may find that the supplement doesn’t work correctly. Many that require to be taken alongside a meal only work for the meal that they are taken with. If you do not take the pill with a meal, it will not work.


Do blood sugar supplements work?

Yes, there are a variety of ingredients that do work to some extent when taken long-term. Cinnamon is the most obvious example of this and has the most scientific research available to back it up. However, other ingredients exist as well, such as berberine. Most supplements out there include one of these ingredients, but this isn’t always necessarily true. Others rely on other ingredients instead, which have varying degrees of effectiveness.

The key to choosing a blood sugar supplement that works is to pay attention to the ingredients. Some are scientifically proven, and some are not. The potency and amounts also matter.

Generally, you should stick with a single supplement for at least three months before calling it off. It can take that long and even longer for it to work correctly.

How can I naturally lower my blood sugar?

Your blood sugar can be lowered best through diet. What you eat has a direct effect on your blood sugar. When you eat foods, they are digested into sugars, which are then absorbed into your bloodstream. This raises your blood sugar. If you eat fewer carbohydrates, your blood sugar will be lower. You can also concentrate on eating foods higher in fiber, as fiber will slow down your digestion and prevent blood sugar spikes.

Another way to slowly lower your blood sugar naturally is to take a blood sugar supplement. These supplements contain ingredients that have been scientifically proven to lower blood sugar levels. Many of these supplements contain things like cinnamon or berberine, which have both lowered blood sugar levels in clinical trials. These supplements are not cures, but they can add to your overall success, especially when paired with a healthy diet.

As a bonus, many of these supplements can also help you lose weight. This may also improve your insulin levels.

What do blood sugar support supplements do?

Blood sugar support supplements work in a variety of ways, depending on the exact ingredients in the supplement. Most help your body’s natural blood sugar regulation systems work even better. They may improve your insulin sensitivity, which makes your body react to less insulin. This helps counteract the effects of diabetes, which does the exact opposite. Sometimes, these supplements may improve the amount of glucose your cells use, effectively lowering your blood sugar.

Others might have secondary effects that help lower your blood sugar over time, like making you feel fuller so that you lose weight. Others include minerals and vitamins to support your hormonal level, which may also affect your insulin levels.

The exact way these supplements work depends on the ingredients. Luckily, they can work in a variety of different ways. Therefore, if one doesn’t work for you, you may be able to switch to a different supplement that works differently.

Can blood sugar supplements reverse diabetes?

No – not by themselves, at least. There is a large variety of ways you can help keep your diabetes in check. Blood sugar supplements are just one of these ways. While they can help lower your fasting blood sugar by a decent amount, they are not a cure. They also work differently depending on the exact cause of your diabetes and what other interventions you’re trying.

They can be a substantial part of a larger plan that includes dietary changes and exercise. Many supplements work great when paired with these more traditional interventions. But they are not going to reverse diabetes all by themselves.

How long does it take for a blood sugar supplement to work?

It usually takes about three months for a blood sugar supplement to reach peak effectiveness. It will likely start working before then, but you probably won’t notice the full effects until around three months of taking the supplement regularly.

Because it takes a decent amount of time before the supplement starts working, it is crucial to stick with a supplement for the full three-month period even if you aren’t noticing much difference.

If you wait for three months and still aren’t happy with the results, consider switching to a different supplement with different ingredients. Different ingredients lower your blood sugar in different ways. So, if one doesn’t work, there is still a decent chance that another one will. Your body just might not have reacted particularly well to the first one you tried.

Do I have to take blood sugar supplements with meals?

Sometimes. Some ingredients work right away for a short period. These ingredients should be taken alongside a meal so that they work on the food you eat. If you take them without eating, the effects will wear off before any food is digested, which results in them doing little to nothing.

Not all supplements work like this, though. Some ingredients work for a decently long amount of time. These supplements can be taken in the morning and work for the rest of the day.

Check the dosage instructions for the particular supplement you’re taking for the best way forward with your supplement. If, when you take pills, is essential to you, be sure to check the dosage instructions before you purchase a supplement.

Related articles


Blood sugar supplements can be part of diabetes or prediabetes management strategies. Many contain scientifically-proven ingredients that may lower your blood sugar, including cinnamon and berberine. These supplements usually take about three months to work, and the degree that they work varies from person to person.

Luckily, there are quite a few different supplements out there. If one doesn’t work, odds are a different one will.

For BodyNutrition’s #1 recommended blood sugar supplement, click here.

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